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Effects of different parameters in caco-2 bi-directional permeability studies

  • In: SIG: Biopharmaceutics Classification System - Posters
  • At: Basel (Switzerland) (2008)
  • Type: Poster
  • Poster code: BCS-P002
  • By: TüRELI, Akif Emre (Across Barriers, SaarbrÜcken, Germany)
  • Co-author(s): Bock, Udo (Across Barriers, SAARBRÜCKEN, Germany)
    Haltner-Ukomadu, Eleonore (Across Barriers, SAARBRÜCKEN, Germany)
  • Abstract:

    Although passive transcellular membrane permeability is one of the major determinants for drugs to be orally absorbed, it is now well established that drug efflux transporters like the multidrug resistance protein MDR1 can significantly effect oral absorption and bioavailability, tissue distribution excretion, pharmacodynamic effects of drugs and..

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Last update 28 September 2023

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