DOSE ADJUSTMENT OF VANCOMYCIN USING CYSTATIN C IN SEPSIS WITH BACTERIAL MENINGITIS: A CASE REPORT

• At: AbuDhabi (United Arab Emirates) (2019)
• Type: Poster
• Poster code: POS-PAA-002
• By: CHUMA, Masayuki (Tokushima University Hospital, Clinical Trial Center for Developmental Therapeutics, Japan)
• Co-author(s): Masayuki Chuma: Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima , Japan
  Masateru Kondo: Department of Pharmacy, Tokushima University Hospital, Tokushima , Japan
  Yoshito Zamami: Department of Pharmacy, Tokushima University Hospital, Tokushima , Japan;Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima , Japan
  Kenshi Takechi: Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima , Japan
  Mitsuhiro Goda: Department of Pharmacy, Tokushima University Hospital, Tokushima , Japan
  Naoto Okada: Department of Pharmacy, Tokushima University Hospital, Tokushima , Japan
  Akitomo Shibata: Department of Pharmacy, Saiseikai Kumamoto Hospital, Kumamoto, Japan
  Mizuho Asada: Department of Pharmacy, Medical Hospital, Tokyo Medical and Dental University, Tokyo, Japan
  Jun Oto: Department of Emergency and Critical Care Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima , Japan
  Hiroaki Yanagawa: Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima , Japan
  Keisuke Ishizawa: Department of Pharmacy, Tokushima University Hospital, Tokushima , Japan;Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima , Japan
  
• Abstract:

  Background

  Vancomycin (VCM) dosing needs to adjust accurately according to therapeutic drug monitoring (TDM) in bacterial meningitis. In determining VCM dosage, renal function is the most important factor. It is necessary to establish VCM dosing regimen that utilize novel marker of renal function because creatinine clearance (CrCl) may not be..

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