DESIGN OF AJULEMIC ACID (AJA)-BASED PARTIAL PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-Ƴ AGONISTS

• At: AbuDhabi (United Arab Emirates) (2019)
• Type: Poster
• Poster code: POS-DDD-011
• By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
• Co-author(s): Kirby Zammit: Pharmacy, University of Malta, Msida, Malta
  Claire Shoemake: Pharmacy, University of Malta, Msida, Malta
  
• Abstract:

  Background

  Ajulemic acid (AJA), a Cannabis sativa analog, has analgesic, muscle relaxing, and anticonvulsant effects. It is a partial PPARγ agonist. Partial PPARγ agonism is advantageous in the management of many conditions including diabetes, producing fewer side-effects than full agonists like the thiazolidenediones which were withdrawn for

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