DESIGN OF NOVEL STEROID RECEPTOR CO-ACTIVATOR (SRC) MODULATORS FOR MALIGNANT DISEASE MANAGEMENT
- At: AbuDhabi (United Arab Emirates) (2019)
- Type: Poster
- Poster code: POS-DDD-007
- By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
- Co-author(s): Ruth Fiorentino: Pharmacy, University of Malta, Msida, Malta
Claire Shoemake: Pharmacy, University of Malta, Msida, Malta - Abstract:
Background
The Steroid Receptor Co-activator (SRC) is overexpressed in several cancer types. There is the consequent expectation that SRC antagonists would mitigate tumour growth. The study by Wang et al. showed paradoxically that SRC overstimulation disrupts tumour homeostasis and proposed experimental molecule MCB-613 as an effective agonist with .. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023