VOLUMETRIC ABSORTIVE MICROSAMPLING: NEW BLOOD COLLECTION METHOD FOR QUANTIFICATION OF TAMOXIFEN
- At: AbuDhabi (United Arab Emirates) (2019)
- Type: Poster
- Poster code: POS-ASP-005
- By: MAGGADANI, Baitha (Universitas Indonesia, Pharmacy, Indonesia)
- Co-author(s): Baitha palanggatan Maggadani: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
Yahdiana harahap: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
Harmita Harmita: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
Marcellino ryan rinaldy: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
Christoffel William Putra Untu: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia - Abstract:
Background
Tamoxifen (TAM) is clinically proven to reduce breast cancer recurrence by blocking estrogen receptor, mainly through its active metabolites, endoxifen (END)and 4-hydroxytamoxifen (4HT) [1]. However, END level showed high variability between patients, widely based on CYP2D6 genetic polymorphism status [2].Methods
20 µL of blood added with .. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023