Pristimerin regulates lipid biogenesis and mtor pathway by activating ampk in colon cancer cells
- At: Glasgow (Scotland) (2018)
- Type: Poster
- Poster code: POS-NPR-022
- By: YOUSEF, Bashir (Faculty of Pharmacy, University of Khartoum, Department of Pharmacology)
- Co-author(s): Bashir Alsiddig Yousef
Hozeifa Hassan
Luyong Zhang
Zhenzhou Jiang - Abstract:
Background
Reprogramming of metabolic pathways and enhancements of lipid biogenesis are important features of colorectal cancer cells (CRC). AMP protein kinase (AMPK) is a metabolic sensor that modulates lipid biosynthetic enzymes and mTOR signaling pathway. Pristimerin, a naturally occurring triterpenoid was previously reported by us to exhibit
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Last update 28 September 2023