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Histaminergic mechanisms and electroshock seizures: some drug interactions in mice

  • In: SIG: Medicinal Chemistry - Posters
  • At: Basel (Switzerland) (2008)
  • Type: Poster
  • Poster code: MC-P-001
  • By: VOHORA, Divya (Jamia Hamdard, New Delhi, New Delhi, India)
  • Co-author(s): Devi, P. Uma (Jamia Hamdard, New Delhi, NEW DELHI, India)
    Manocha, Anshu (Jamia Hamdard, New Delhi, NEW DELHI, India)
  • Abstract:

    Several lines of evidence, both experimental and clinical, have indicated an anticonvulsant action of endogenous histamine. N-acetylcysteine, an antioxidant, is reported to enhance the release of histamine from mast cells. We have earlier reported additive/ synergistic effects of antioxidant drug (NAC) with antiepileptic drugs phenytoin (PHT) and..

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Last update 28 September 2023

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