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Modernized traditional Chinese medicine significantly inhibit hepatic enzymes -- address to the risk of herb-drug interactions

  • In: SIG Natural Substances - Posters
  • At: Beijing (China) (2007)
  • Type: Poster
  • Poster code: NS-P-106
  • By: HU, Oliver Yoa-Pu (National Defense Medical Center, Taipei, China Taiwan)
  • Co-author(s): Hsiong, Cheng-Huei (National Defense Medical Center, TAIPEI, China Taiwan)
    Pao, Li-Heng (National Defense Medical Center, TAIPEI, China Taiwan)
    Hung, Chi-Fung (National Defense Medical Center, TAIPEI, China Taiwan)
  • Abstract:

    Aims: To evaluate the metabolic effects and the potential herb-drug interactions for modernized traditional Chinese medicine (TCM). Methods: A cocktail contained with human liver microsome and was consisted of CYP- and UGT-selective probes: ethoxyresorufin (CYP1A2), dextromethophan (CYP2D6), testosterone (CYP3A4), tolbutamide (CYP2C9) and morphine


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Last update 4 October 2019

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