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In vitro and in vivo studies of inhibition of hepatic enzymes to address the risk of herb-drug interactions

  • In: SIG Natural Substances - Posters
  • At: Beijing (China) (2007)
  • Type: Poster
  • Poster code: NS-P-105
  • By: HU, Oliver Yoa-Pu (National Defense Medical Center, Taipei, China Taiwan)
  • Co-author(s): Hsiong, Cheng-Huei (National Defense Medical Center, TAIPEI, China Taiwan)
    Pao, Li-Heng (National Defense Medical Center, TAIPEI, China Taiwan)
    Hung, Chi-Fung (National Defense Medical Center, TAIPEI, China Taiwan)
  • Abstract:

    Aims:To evaluate the metabolic effects and the potential herb-drug interactions for traditional Chinese medicine (TCM). Methods:A cocktail contained with human liver microsome and was consisted of CYP- and UGT-selective probes: ethoxyresorufin (CYP1A2), dextromethophan (CYP2D6), testosterone (CYP3A4), tolbutamide (CYP2C9) and morphine (UGT2B7)...

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Last update 28 September 2023

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