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Effects of tetramethylpyrazine, ginsenoside rg1 and their combination on p-gp function and expression in caco-2 cells

  • In: SIG Pharmaceutical Biotechnology - Posters
  • At: Beijing (China) (2007)
  • Type: Poster
  • Poster code: PB-P-027
  • By: SONG, Juan (The second Xiangya Hospital, Changsha, China)
  • Co-author(s): Liu, Xiaolei (The second Xiangya Hospital, CHANGSHA, China)
    He, Juan (The second Xiangya Hospital, CHANGSHA, China)
    Tang, Jing (The second Xiangya Hospital, CHANGSHA, China)
  • Abstract:

    AIM: To study the effect of tetramethylpyrazine and/or ginsenoside Rg1 on the activity of p-glycoprotein in Caco-2 cells. METHODS: HPLCâ€'UV was used to detect the concentration of rhodamine 123, flow cytometry was used to analysis the expression of p-glycoprotein in Caco-2 cell monolayers. RESULTS: Middle and high dose of tetramethylpyrazine..

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Last update 28 September 2023

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