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Synthesis, structure , antitumor activity and mechanism of a new diorganotin ( iv ) complex with arylhydroxamate [ (n-bu)2sn(c7h5o2ncl)cl ]

  • In: SIG Pharmaceutical Biotechnology - Posters
  • At: Beijing (China) (2007)
  • Type: Poster
  • Poster code: PB-P-025
  • By: LI, Yunlan (Shanxi Medical University, Shanxi, China)
  • Co-author(s): YANG, Li (Shanxi Medical University, SHANXI, China)
    NIU, Xiao-Qiang (Shanxi Medical University, SHANXI, China)
    LIANG, Tai-Gang (Shanxi Medical University, SHANXI, China)
  • Abstract:

    OBJECTIVE: To synthetize a new diorganotin ( IV ) complex and study its antitumor activities in vivo and in vitro and action mechanism . METHODS: Reaction of di-n-butyltin ( IV ) dichloride with 4-chlorobenzohydroxamic acid yielded a new mixed-ligand diorganotin ( IV ) complex. Use Kunming mice as transplantable carcinomas animal models. The..

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Last update 28 September 2023

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