Potassium channel related mechanisms of mpp+-induced cell death in wild type and alpha-synuclein-transfected sh-sy5y
- In: SIG Pharmaceutical Biotechnology - Posters
- At: Beijing (China) (2007)
- Type: Poster
- Poster code: PB-P-003
- By: SHI, Qiaoqiao (Institute of Materia Medica, Beijing, China)
- Co-author(s): Wang, Xiaoliang (Institute of Materia Medica, BEIJING, China)
Aim: To investigate the mechanisms of the dopaminergic neurons death in Parkinson Disease (PD), we studied the roles of the potassium channel in MPP+-induced cell death in wild type and alpha-synuclein-transfected SH-SY5Y. Methods: Wild type (WT) and A53T mutant alpha-synuclein-transfected SH-SY5Y were exposed to MPP+ (1-methyl-4-phenylpyridinium) .. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.