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Potassium channel related mechanisms of mpp+-induced cell death in wild type and alpha-synuclein-transfected sh-sy5y

  • In: SIG Pharmaceutical Biotechnology - Posters
  • At: Beijing (China) (2007)
  • Type: Poster
  • Poster code: PB-P-003
  • By: SHI, Qiaoqiao (Institute of Materia Medica, Beijing, China)
  • Co-author(s): Wang, Xiaoliang (Institute of Materia Medica, BEIJING, China)
  • Abstract:

    Aim: To investigate the mechanisms of the dopaminergic neurons death in Parkinson Disease (PD), we studied the roles of the potassium channel in MPP+-induced cell death in wild type and alpha-synuclein-transfected SH-SY5Y. Methods: Wild type (WT) and A53T mutant alpha-synuclein-transfected SH-SY5Y were exposed to MPP+ (1-methyl-4-phenylpyridinium) ..

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Last update 28 September 2023

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