Pharmacogenetics of drug-metabolising enzymes: implications for a safer drug therapy

• In: C2 - Individualisation of Drug Therapy and Ethical Concerns on Saturday, 5 September 2009, 14:00-17:00
• At: Istanbul (Turkey) (2009)
• Type: Presentation
• By: YASAR, Umit (Hacettepe University, Faculty of Medicine, Department of Pharmacology, Ankara, Turkey)
• Co-author(s): O. Babaoglu, Melih (Hacettepe University, Faculty of Medicine, Department of Pharmacology, ANKARA, Turkey)
  Bozkurt, Atilla (Hacettepe University, Faculty of Medicine, Department of Pharmacology, ANKARA, Turkey)
  Kayaalp, S. Oguz (Hacettepe U. Dept. of Pharmacology & Turkish Academy of Science, member emeritus, Turkey)
  
• Abstract:

  The safety and efficacy of drug therapy are influenced by many factors, such as age, weight, comorbidity, comedication and genetic variations. Patients vary widely in response to drug treatment. Slow and ultrarapid metaboliser individuals are under increased risk for adverse drug reactions or treatment failure. Drug metabolising enzymes are

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