Native-American contribution in Puerto Ricans is associated with a lower warfarin dose requirement

• In: Short oral presentations, Part 1 (Industry & Science) on Monday, 29 August 2016, 17:00-17:15
• At: Buenos Aires (Argentina) (2016)
• Type: Presentation
• By: CLAUDIO, Karla (University of Puerto Rico, Pharmacology and Toxicology, San Juan, Puerto Rico)
• Co-author(s): Karla Claudio:|Carmen Cadilla:Biochemistry,University of Puerto Rico,San Juan,Puerto Rico|Jorge Duconge:Pharmaceutical Sciences,University of Puerto Rico,San Juan,Puerto Rico
  
• Abstract:

  Backgrounds: Warfarin is an oral anticoagulant that requires monitoring to avoid adverse drug reactions. Variability in warfarin dose requirements can be explained by clinical and genetic determinants. Puerto Ricans are admixed and heterogeneous having Caucasian, African and Native-American contributions.

  Purpose: We hypothesized that admixture is

  ..

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