Expression and function of a peptide transporter pept2 in alveolar epithelial cells in culture

• In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PG-009
• By: YUMOTO, Ryoko (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
• Co-author(s): Sugimoto, Natsumi (Hiroshima University, Hiroshima, Japan)
  Sasaki, Yoshihiro (Hiroshima University, Hiroshima, Japan)
  Yamamoto, Chieko (Hiroshima University, Hiroshima, Japan)
  Nagai, Junya (Hiroshima University, Hiroshima, Japan)
  Ehrhardt, Carsten (Trinity College Dublin, Dublin, Ireland)
  Takano, Mikihisa (Hiroshima University, Hiroshima, Japan)
  
• Abstract:

  Backgrounds: In the lungs, various uptake transporters including PEPT2 are expressed, and PEPT2 would be an attractive target for the pulmonary absorption of inhaled drugs. The alveolar region of the lungs is composed of type II and type I epithelial cells. Recently, we have reported that PEPT2 is functionally expressed in primary cultured type II ..

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