Gene therapy: pegylation of cationic dna lipoplexes can increase the distribution and transfection efficiency in the muscle

• In: Posters B- Biotechnology (Vaccine)
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PB-002
• By: HO, Joan (Monash University, Drug Discovery Biology, Melbourne, Australia)
• Co-author(s): White, Paul (Monash University, Melbourne, Australia)
  Pouton, Colin (Monash University, Melbourne, Australia)
  
• Abstract:

  Background Genetic diseases of the skeletal muscle, such as muscular dystrophy, can lead to the progressive weakening and degeneration of the muscle. Gene therapy has been trialled as a treatment option; however, due to the poor transfection efficiency of plasmid DNA in the muscle, the effectiveness of this therapy is still relatively low. Aim Our

  ..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login