Menu
  • Join
  • Login
  • Contact
 

Search abstracts / presentations


Design, synthesis, and biological evaluation of memantine-polyamine conjugates as NMDA channel blockers

  • In: SIG Posters
  • At: Amsterdam (the Netherlands) (2012)
  • Type: Poster
  • Poster code: DDD-P-14
  • By: KUMAMOTO, Takuya (Musashino University, Faculty of Pharmaceutical Sciences, Nishitokyo, Japan)
  • Co-author(s): Yoshizawa, Y. (Chiba University, Chiba, Japan)
    Higashi, K. (Chiba University, Chiba, Japan)
    Nishimura, K. (Chiba University, Chiba, Japan)
    Toida, K. (Chiba University, Chiba, Japan)
    Ishikawa, T. (Chiba University, Chiba, Japan)
    Katakawa, K. (Musashino University, Nishitokyo, Japan)
    Igarashi, K. (Amine Pharma, Chiba, Japan)
  • Abstract:

    1. Background
    N

    -Methyl-D-aspartate (NMDA) receptors have been implicated in learning and memory, and may also play a central role in various conditions leading to neuronal degradation. Overexcitation of NMDA receptors may result in neuronal cell injury or death. Therefore, NMDA receptor antagonists could be of therapeutic benefit to a number of

    ..

  • The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 28 September 2023

FIP Congresses