Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in Chinese population

• In: Clinical Biology Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: CBS-P-005
• By: LI, Huan-De (The second xiangya hospital of central south university, Changsha, Hunan, China)
• Co-author(s): Xu, Ping (The second xiangya hospital of central south university, CHANGSHA, HUNAN, China)
  
• Abstract:

  Among the studies on the influence of MDR1 SNPs on drug metabolism, SNPs in exon 12 (C1236T), 21(G2677T/A) and 26(C3435T) are the most extensively studied SNP polymorphisms. It is interesting that the synonymous SNP at exon 26 has been considered the most likely variant to be associated with altered protein expression and drug metabolism, the

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