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Conjunctival drug permeability, employing QSPR and PK models

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-B-106-Tuesday
  • By: RAMSAY, Eva (University of Eastern Finland, School of Pharmacy, Helsinki, Finland)
  • Co-author(s): Eva Ramsay: School of Pharmacy, University of Eastern Finland, Kuopio, Finland;Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
    Theo Picardet: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Eva M. del Amo: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Unni Tengvall: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Seppo Auriola: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Elisa Toropainen: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Marika Ruponen: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Arto Urtti: School of Pharmacy, University of Eastern Finland, Kuopio, Finland;Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
  • Abstract:

    Backgrounds

    Topical administration on the ocular surface is followed by large fraction of the dose to be absorbed across the conjunctiva to the systemic blood circulation, due to larger surface area and leakier membrane of the conjunctiva than that of cornea. However, systematic studies of conjunctiva as permeation barrier for small molecular drugs

    ..

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Last update 28 September 2023

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