Menu
  • Join
  • Login
  • Contact
 

Search abstracts / presentations


Evaluation of transport of tyrosine kinase inhibitors across the blood-brain barrier in the pericyte-deficient state

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-A-087-Monday
  • By: MIHAJLICA, Nebojsa (Uppsala University, Pharmaceutical Biosciences, Uppsala, Sweden)
  • Co-author(s): Nebojsa Mihajlica: Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
    Christer Betsholtz: Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
    Margareta Hammarlund-Udenaes: Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
  • Abstract:

    Backgrounds

    Pericytes play an important role in the maintenance of blood-brain barrier (BBB) transport properties. Tyrosine kinase inhibitors (TKIs) are drugs which have limited transport across the functional BBB, mainly due to active efflux processes.

    Aims

    To evaluate the role of pericytes in BBB transport, by assessing several TKIs in a

    ..

  • The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 28 September 2023

FIP Congresses