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Addition of an absorption sink to the in vitro digestion model leads to an improved understanding of drug absorption from oral lipid-based delivery systems

  • In: Posters: Formulation Design and Pharmaceutical Technology
  • At: Bangkok (Thailand) (2014)
  • Type: Poster
  • Poster code: POS-FDP003
  • By: CRUM, Matthew (Monash Institute of Pharmaceutical Sciences, Victoria, Australia)
  • Co-author(s): Williams, Hywel (Monash Institute of Pharmaceutical Sciences, Victoria, Australia)
    Pouton, Colin (Monash Institute of Pharmaceutical Sciences, Victoria, Australia)
    Porter, Christopher (Monash Institute of Pharmaceutical Sciences, Victoria, Australia)
  • Abstract:

    BackgroundOne of the limitations to the more widespread use of lipid-based formulations in oral drug delivery is an incomplete understanding of the influence of lipid digestion on the rate and extent of drug absorption. Here an in vivo model was developed that incorporates simulated lipid digestion and drug absorption in anaesthetised rats.
    AimsTo ..

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Last update 28 September 2023

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