SIG on Pharmacokinetics / Pharmacodynamics (PK/PD), Absorption, Distribution, Metabolism and Excreti

Chair: Dr Don Mager (USA)

Vice-Chairs: Prof. Hiroshi Suzuki (Japan) & Dr Masoud Jamei (United Kingdom)

The intensity and time-course of pharmacological effets (pharmacodynamics, PD) are the results of the complex interplay between drug- and system specific properties.

The time-course of drug concentrations (pharmacokinetics, PD) represents the driving force for the response to drugs, and major processes regulating drug exposure include absorption, distribution, metabolism and excretion (ADME).

Clinical outcomes ultimately reflect PK/PD relationships that can be influenced by numerous pharmacological and (patho-)physiological factors.

The PK/PD & ADME SIG provides an international forum for the development and evaluation of methodologies that seek to translate PK/PD principlesfor the optimization of pharmaceutical care. Our goal is to bring together scientists engaged in ADME and PK/PD research with clinical pharmacists to foster collaborations and facilitate the generation and dissemination of new approaches for advancing pharmacotherapy.

We also recognize education and training as a core component of this SIG and are working toward educational opportunities for our glbal members and recruitment strategies through state-of-the-art programming at the Annual FIP congress, as well as new electronic and online platforms.