Benzo[a]carbazoles inhibitors of 4t1 malignant cells growth

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: MARTIARENA, Jorge (School of Pharmacy, Biological Chemistry, Buenos Aires, Argentina)
  • Co-author(s): Jorge Luis Martiarena:
    Maximiliano Reybet: Biological Chemistry, School of Pharmacy, Buenos Aires, Argentina
    Diego Cóbice: Metabolomics and Proteomics Clinical Biochemistry and Molecular Analyses, Ulster University, Belfast, Ireland
  • Abstract:

    Methods

    G1 was synthesized starting from 1,4-diBr-2-F-benzene precursor to obtain  intermediates A2 and B, both combined yielded G1.

    In order to assay the inhibition efficiency of G1, viability experiments were performed with 4T1 malignant cells culture incubated for 24 hs

    Results

    G1 showed moderate growth inhibition at 24 hs incubated with
    ..

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