Novel topical nano-carriers to improve penetration of tacrolimus into the skin

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: OZSOY, Yıldız (Turkey)
  • Co-author(s): Emine Kahraman
    Neşet Neşetoğlu
    Sevgi Güngör
    Dürişehvar Ünal
    Yıldız Özsoy
  • Abstract:

    Methods

    The polymeric micelles were prepared by thin film hydration method. Encapsulation efficiency (EE) were determined using Centrifuge Process and HPLC. The penetration of tacrolimus in the skin was detected by tape stripping method and LC/MS.

    Results

    EE of oleic acid containing polymeric micelles was found more than 99 %. Tape stripping data..

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