Epigenetic modification of cryptotanshinone in activating nrf2 and inhibiting dna methyltransferases and histon deacetylases

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: WU, Tien-Yuan (Tzu Chi University, Pharmacology, Hualien, China Taiwan)
  • Co-author(s): Rachmad Anres Dongoran: Pharmacology, Tzu Chi University, Hualien, Taiwan, Province of China
    Yun-Syuan Chen: Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, Taiwan, Province of China
    Tien-Yuan Wu: Pharmacology, Tzu Chi University, Hualien, Taiwan, Province of China
  • Abstract:

    Background

    Cryptotanshinone is one of the major tanshinones compound isolated from Salvia miltiorrhiza Bunge to treat many kinds of diseases including cancers. Epigenetic alterations are much more frequent in some types of cancer cells than genetic (mutational) alterations, more importantly, the epigenetic impact of cryptotanshinone has not been..

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