Antitumor activity of spicatoside a, a steroidal saponin, is associated with induction of autophagy and apoptotic cell death

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: KIM, Wonkyung (Seoul National University, College of Pharmacy, Korea, Republic Of)
  • Co-author(s): Wonkyung Kim: College of Pharmacy, Seoul National University,
    Yuna Pyee: College of Pharmacy, Seoul National University, Korea, Republic Of
    Hyen Joo Park: College of Pharmacy, Seoul National University, Korea, Republic Of
    Ji-Young Hong: College of Pharmacy, Seoul National University, Korea, Republic Of
    Sang Kook Lee: College of Pharmacy, Seoul National University, Korea, Republic Of
  • Abstract:

    Background

    Spicatoside A (SA), isolated from the tubers of Liriope platyphylla, has been reported to have anti-osteoarthritic and anti-inflammatory activities. However, the antitumor potential and its underlying mechanism of action against human cancer cells have not been elucidated yet.

    Purpose

    The antitumor activity of SA and its underlying..

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