Zein nanoparticles loaded with vorinostat and bortezomib combination for synergistic anticancer effects in metastatic prostate cancers

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Jong Seong Lee: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Raj Kumar Thapa: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Hanh Thuy Nguyen: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Min Hyun Sung: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jee-Heon Jeong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han-Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Methods

    ZNP/VB was prepared using the phase separation method. The nanoparticles were then optimized and characterized, and their potential effects in the treatment of prostate cancer were studied in vitro and in vivo.

    Results

     Our results revealed the successful preparation of ZNP/VB with a small particle size (~160 nm) and polydispersity index..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login