Development of silver nanoparticles decorated graphene oxide-methotrexate for targeted cancer therapy

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Jae Hee Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Raj Kumar Thapa: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Young-Im Lee: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jae-Myung Lee: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Methods

    The characterization of the prepared MTX-GO/AgNPs was performed with UV/visible spectroscopy, TEM, AFM, FTIR and XRD analysis. Evaluation of cellular uptake, cytotoxicity and apoptosis induction by MTX-GO/AgNPs in MCF-7 and HepG2 cells were performed using confocal imaging, FACS and western blot analysis.

    Results

    Successful formation of..

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