Low-frequency ultrasound facilitated transdermal delivery of asenapine maleate

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: MANIKKATH, Jyothsna (Manipal College of Pharmaceutical Sciences, Pharmaceutics, Manipal, India)
  • Co-author(s): Jyothsna Manikkath: Dept of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
    Srinivas Mutalik: Dept of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  • Abstract:

    Methods

    Asenapine maleate was subjected to passive diffusion and ultrasound-assisted ex vivo skin permeation studies using skin from male Sprague Dawley rats. The experiments were conducted in two modes, viz., treatment of skin with ultrasound, followed by passive diffusion of drug dispersion (pretreatment mode) or application of ultrasound and..

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