Protective effect of curcumin nanoparticles against aluminum chloride-induced alzheimer's disease

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: AMIRTHALINGAM, Muthukumar (Manipal College of Pharmaceutical Sciences, Pharmaceutics, Manipal,Karnataka, India)
  • Co-author(s): Muthukumar Amirthalingam: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India
    Nayanabrahma Udupa: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India
  • Abstract:

    Methods

    PLGA nanoparticles were prepared by nanoprecipitation technique. The in vitro dissolution study was carried out for 144 h. The cell uptake study of the nanoparticles was carried out in the SH-SY5Y cell line. The curcumin content in the brain was analysed by HPLC and the brain histology evaluation was carried out in the AlCl3-induced..

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