Development of a model-based dose-individualisation approach with an application to routine clinical data

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Presentation
  • By: GUK, Jinju (Yonsei University College of Medicine, Seoul, Korea, Republic Of)
  • Co-author(s): Jinju Guk
    Dongwoo Chae
    Kyungsoo Park
  • Abstract:

    With the development of new effective antiepileptic agents, the use of phenytoin has kept decreasing. Large inter-individual variability and narrow therapeutic range in drug concentration is another reason for decrease in phenytoin use. However, phenytoin is still an essential agent for second-line treatment of status epilepticus when patients do

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